Activo-P11 Automated Peptide Synthesizer

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The Activo-P11 Peptide Synthesizer is an easy to use and affordable instrument for synthesis of very high quality peptides. The Activo-P11 is the only synthesizer available with both automated reactor heating and UV monitoring. These valuable synthesis tools allow chemists to synthesize longer and more difficult peptides and to gain more synthesis information about those peptides. For example the antimicrobial peptide Gomesin has been successfully synthesized using conventional heating, click here

New Automated Peptide Synthesis with UV Monitoring

New ActivoPep™ Software Release for the P11 Peptide Synthesizer - click here for details

Activo-P11  Automated Peptide Synthesizer

Key Features

  • High quality peptides
  • Any scale from 0.05 to 5.0 mmol
  • Easy to use; define own protocols or use the peptide wizard software
  • Performs any Fmoc or t-Boc chemistries
  • PNA synthesis
  • Safe to use, instrument is totally enclosed
  • Fully automatic with no limit to number of amino acids
  • Disposable reactors and amino acid containers
  • Uses commercially available resins and reagents

software

User friendly software

heated-reactor-400wide

Heated reactor
• Ambient to +70 °C
• Cooling
• Increased coupling efficiency

Installation of reactors

Easy installation and removal of reactors

Efficient mixing of reactors

Efficient mixing of reactors

 

High Quality Peptide

  • Inert atmosphere throughout
  • Precise and fast reagent delivery and washing
  • Efficient inversion mixing
  • Bottom filtration from disposable reactors
  • Fresh amino acids in powder
  • Pre-activation vessel
  • Multi-tasking
  • Heated reactors
  • UV monitoring

Chemistry

  • Fmoc or t-Boc
  • PNA synthesis
  • In situ or preactivation
  • Use any coupling reagents; HBTU, HCTU, HATU, TBTU, PyBOP, DIC etc
  • Use any resins; polystyrene or PEG based supports
  • Use any protocols
  • Synthesize any length of peptides

Ease of Use

  • Very easy to use software; import the sequence, fill in quantity and resin specifications then press run
  • Software generated worksheet tells the user what to prepare
  • Free choice of chemistry, present and future
  • Disposable reactors and amino acid containers
  • 60 amino acid containers, no limit to how many can be added
  • Enclosed cabinet for safe bench top use
  • Easy cleave system direct from the disposable reactor
  • Logfile of each synthesis
  • Easy cleavage on the machine or transfer disposable reactor to the Activo-P12 Cleavage Device

Technical Support

Activotec has been supplying quality custom peptides for many years, we have unsurpassed experience in the synthesis and automation processes. The Activo-P11 is used in both our peptide production and our peptide research facilities. Activotec is totally committed to supporting its customers worldwide.

  • Fast reliable service engineers and application chemists.
  • Service contract options are available to suit your requirements.
  • Peptide chemists are available to help with instrument application and peptide chemistry if required.
  • Training is provided on site or in our facility.

Dimensions

W - 84cm or 33in D - 59cm or 23in H - 70cm or 28in

 

The Activo-P11 peptide synthesizer has been very successful in our laboratory producing quality peptides with good yields. - Dr Peter Fojan, University Aalborg, Denmark

 

Instrument Specification

Scale   0.05 to 5.0 mmol
Chemistry   Fmoc or t-Boc
Dissolve dry amino acids or use pre dissolved
Activation method   Pre-activation or in situ, user selectable. HBTU, HCTU, COMU, DIC, PyBop etc
Amino acid vessels   60 of 15 mL or 30 of 50 mL arranged in a carousel so no limit
Reaction vessel sizes   10 mL, 40 mL and 125 mL
Reagent/solvent bottles   9, range from 250 mL to 19 litres
2 of 10 litres each
Mixing system   Over centre mixing with variable speed and amplitude
Inert atmosphere   100% throughout the system
Fluid measurement   Fill loops for calibration free measurement of reagents
Timed delivery for washing solvents
Power   Variable range from 240V/50 Hz to 100V/ 60 Hz
Safety   CE marked, system enclosed with door interlock
Ventilation   Designed for bench top use with extractor attached
Logfile   Printable logfile for each synthesis run
Software   User friendly interface, pre-written protocols or user defines own
Controller   Desktop PC
Temperature   Ambient to +70 ºC
Dimensions   Width 84 cm (33"), depth 60 cm (23"), height 70 cm (28")

Download the user manual here

sequence graphs

 

New Automated Peptide Synthesis with UV Monitoring

UV monitoring
Fresh amino acids and preactivation vessel

Fresh amino acids and preactivation vessel

10 mL or 40 mL throw away reactors

10 mL or 40 mL
throw away reactors

 

 

 

 

 

 

Activo-P12 Cleavage Device

p12-contoured

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Do you need more information?

For more details on any of our products and services please telephone: +44 (0)1223 260008 or you can request information using our enquiry form.
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