The Activo-PLS parallel reaction synthesizer provides an economic and easy to use parallel synthesis tool to accelerate your chemistry research.


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Activo-PLS RapiCool™ now available on PLS24 & PLS6!

The Activo-PLS parallel reaction synthesizer provides an economic and easy to use parallel synthesis tool to accelerate your chemistry research. Enabling fast lead generation, optimization, process development, combinatorial catalysis etc utilizing a range of PTFE solid phase and glass solution phase reactors.

Can be used for low cost multiple peptide synthesis too!

  • Solution phase chemistry and/or solid phase chemistry
  • Multiple peptide synthesis
  • Scales from 0.5 mL to 50 mL
  • Vortex mixing – variable speed
  • Heating to +150°C, cooling to -80°C
  • Suzuki reactions, amide bond formation, reductive aminations etc etc
  • Parallel washing, product retrieval and cleavage

Parallel Reactor Reactor configuration options:

 

Activo-PLS Type  Max. Heating  Min.  Cooling  No. of temp. zones  No. of reactors places  Reaction volume range  Max Vial/Reactor diameter  Solid or solution phase capable 
PLS4x6  Y+150°C  N  4  24  0.5mL – 6.0mL  17.1 mm  Both 
PLS4x4  Y+150°C  N  4  16  2.0mL – 14.0mL  27.8 mm  Both 
PLSHybrid  Y+150°C  N  4  20 – 2 rows of 6, 2 rows of 4  0.5mL – 14.0mL  17.1mm and 27.8mm   Both 
PLS50  Y+70°C  N  4  4  30mL in a 50mL reactor  n/a  Solution 
PLS24  Y+150°C  Y -80°C  1  24  0.5mL – 6.0mL  17.1 mm  Both 
PLS6  Y+150°C  Y -80°C  1  6  10.0mL – 50mL  40.5mm  Both 
PLS4x6, PLS4x4 and PLS50 reactor blocks can be interchanged on the same base. 
PLS24 and PLS6 reactor blocks can be interchanged on the same base. 

 

PLS4x6

  • 4 rows with individual temperature control from room temperature to +150°C
  • Synthesis scale from 0.5 mL to 5 mL

PLS4x4

  • 4 rows with individual temperature control from room temperature to +150°C
  • Synthesis scale up to 20 mL

parallel reaction synthesizer

PLS50

  • 4 rows with individual temperature control from room temperature to +150°C
  • 4 x 50mL round bottom flasks

parallel reaction synthesizerparallel reaction synthesizer

PLS24 – cool to -80°C in just 20 mins!!

  • Heating and cooling from -80°C to +150°C
  • Dry box prevents any ice formation on cooling
  • Synthesis scale from 0.5 mL to 5 mL

PLS6 – cool to -80°C in just 20 mins!!

  • Heating and cooling from -80°C to +150°C
  • Dry box prevents any ice formation on cooling
  • Synthesis scale up to 50 mL

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