Automated Peptide Synthesizer

The Activo-P11 is one of the only automated peptide synthesizer available with both automated reactor heating and UV monitoring. These valuable synthesis tools allow chemists to synthesize longer and more difficult peptides and to gain more synthesis information about those peptides. For example the antimicrobial peptide Gomesin has been successfully synthesized using conventional heating.

The most reliable and lowest running cost synthesizer available. Compatible with green chemistry solvents.

New Automated Peptide Synthesizer with UV Monitoring

New ActivoPep Software Release for the P11 Peptide Synthesizer – click here for details

Activo-P11 Brochure download

Activo-P11 UV Monitoring Brochure download

Activo-P11 Automated Peptide Synthesizer

Key Features

High quality peptides
Any scale from 0.005 to 5.0 mmol
Easy to use; define own protocols or use the peptide wizard software
Performs any Fmoc or t-Boc chemistries
Compatible with green chemistry protocols and reagents
PNA synthesis
Safe to use, instrument is totally enclosed
Fully automatic with no limit to number of amino acids
Disposable reactors and amino acid containers
Uses commercially available amino acids, resins and reagents
Self diagnostics with fluidic sensors checking reagent delivery, emptying and transfers

High Quality Peptide

Inert atmosphere throughout
Precise and fast reagent delivery and washing
Efficient inversion mixing
Bottom filtration from disposable reactors
Fresh amino acids in powder
Pre-activation vessel
Multi-tasking
Heated reactors
UV monitoring

Chemistry

Fmoc or t-Boc
PNA synthesis
In situ or preactivation
Use any coupling reagents; HBTU, HCTU, HATU, TBTU, PyBOP, DIC etc
Green chemistry compatible hardware and software
Use any resins; polystyrene or PEG based supports
Use any protocols
Synthesize any length of peptides

Ease of Use

Very easy to use software; import the sequence, fill in quantity and resin specifications then press run
Software generated worksheet tells the user what to prepare
Free choice of chemistry, present and future
Disposable reactors and amino acid containers
60 amino acid containers, no limit to how many can be added
Enclosed cabinet for safe bench top use
Logfile of each synthesis
Easy cleavage on the machine or transfer disposable reactor to the Activo-P12 Cleavage Device

Technical Support

Activotec has been supplying quality custom peptides for many years, we have unsurpassed experience in the synthesis and automation processes. The Activo-P11 is used in both our peptide production and our peptide research facilities. Activotec is totally committed to supporting its customers worldwide.

Fast reliable service engineers and application chemists.
Service contract options are available to suit your requirements.
Peptide chemists are available to help with instrument application and peptide chemistry if required.
Training is provided on site or in our facility.

Dimensions

W – 84cm or 33in D – 59cm or 23in H – 70cm or 28in

Automated Peptide Synthesizer Heated reactors with real time temperature feedback Heated reactor
• Ambient to +90 °C
• Increased coupling efficiency

Easy installation and removal of reactors

Efficient mixing of reactors

Instrument Specification

Scale		0.005 to 5.0 mmol
Chemistry		Fmoc or t-Boc Dissolve dry amino acids or use pre dissolved
Activation method		Pre-activation or in situ, user selectable. HBTU, HCTU, COMU, DIC, PyBop etc
Amino acid vessels		60 of 15 mL or 30 of 50 mL arranged in a carousel so no limit
Reaction vessel sizes		10 mL, 40 mL and 125 mL
Reagent/solvent bottles		9, range from 250 mL to 19 litres 2 of 10 litres each
Mixing system		Over centre mixing with variable speed and amplitude
Inert atmosphere		100% throughout the system
Fluid measurement		Fill loops for calibration free measurement of reagents Timed delivery for washing solvents
Power		Variable range from 240V/50 Hz to 100V/ 60 Hz
Safety		CE marked, system enclosed with door interlock
Ventilation		Designed for bench top use with extractor attached
Logfile		Printable logfile for each synthesis run
Software		User friendly interface, pre-written protocols or user defines own
Controller		Desktop PC
Temperature		Ambient to +90 ºC
Dimensions		Width 84 cm (33″), depth 60 cm (23″), height 70 cm (28″)