Activo-PLS RapiCool™ now available on PLS24 & PLS6!
The Activo-PLS parallel reaction synthesizer provides an economic and easy to use parallel synthesis tool to accelerate your chemistry research. Enabling fast lead generation, optimization, process development, combinatorial catalysis etc utilizing a range of PTFE solid phase and glass solution phase reactors.
Can be used for low cost multiple peptide synthesis too!
- Solution phase chemistry and/or solid phase chemistry
- Multiple peptide synthesis
- Scales from 0.5 mL to 50 mL
- Vortex mixing – variable speed
- Heating to +150°C, cooling to -80°C
- Suzuki reactions, amide bond formation, reductive aminations etc etc
- Parallel washing, product retrieval and cleavage
Parallel Reactor Reactor configuration options:
| Activo-PLS Type | Max. Heating | Min. Cooling | No. of temp. zones | No. of reactors places | Reaction volume range | Max Vial/Reactor diameter | Solid or solution phase capable |
| PLS4x6 | Y+150°C | N | 4 | 24 | 0.5mL – 6.0mL | 17.1 mm | Both |
| PLS4x4 | Y+150°C | N | 4 | 16 | 2.0mL – 14.0mL | 27.8 mm | Both |
| PLSHybrid | Y+150°C | N | 4 | 20 – 2 rows of 6, 2 rows of 4 | 0.5mL – 14.0mL | 17.1mm and 27.8mm | Both |
| PLS50 | Y+70°C | N | 4 | 4 | 30mL in a 50mL reactor | n/a | Solution |
| PLS24 | Y+150°C | Y -80°C | 1 | 24 | 0.5mL – 6.0mL | 17.1 mm | Both |
| PLS6 | Y+150°C | Y -80°C | 1 | 6 | 10.0mL – 50mL | 40.5mm | Both |
PLS4x6, PLS4x4 and PLS50 reactor blocks can be interchanged on the same base.
PLS24 and PLS6 reactor blocks can be interchanged on the same base.
PLS4x6
- 4 rows with individual temperature control from room temperature to +150°C
- Synthesis scale from 0.5 mL to 5 mL
PLS4x4
- 4 rows with individual temperature control from room temperature to +150°C
- Synthesis scale up to 20 mL
PLS50
- 4 rows with individual temperature control from room temperature to +150°C
- 4 x 50mL round bottom flasks
PLS24 – cool to -80°C in just 20 mins!!
- Heating and cooling from -80°C to +150°C
- Dry box prevents any ice formation on cooling
- Synthesis scale from 0.5 mL to 5 mL
PLS6 – cool to -80°C in just 20 mins!!
- Heating and cooling from -80°C to +150°C
- Dry box prevents any ice formation on cooling
- Synthesis scale up to 50 mL