Fmoc-L-Amino Acids were first reported by Carpino in 1970. Peptide synthesis and cleavage conditions are milder with Fmoc amino acids than Boc amino acids. This protecting group offers also more flexibility for the modification of the peptide chain and more specificity in the cleavage of the side-chain protecting groups.

The Fmoc group is removed from Fmoc-peptide chain under basic conditions, thus allowing any acid labile resins to be used. The Fmoc group is usually removed using piperidine, which removes the Fmoc group and reacts with the deprotection byproduct, the dibenzofulvene, to prevent undesired side reactions and byproducts. This dibenzofulvene adduct allows the UV monitoring of the deprotection progression to be performed.

 

The Fmoc group has a limited stability towards tertiary amines such as DIEA, pyridine, this stability depends on base concentration, solvent and temperature.

Please click on the amino acid name to see the detailed description and CAS number.

All Fmoc-L-Amino Acids are also available in bulk quantities, please get in touch or request a quotation.

Product

Prod. code / CAS#

Structure

Product

Fmoc-Ala-OH*H2O

more information

Prod. code / CAS#

FLA-01
35661-39-3

Structure

100g

£48.00

€57

$63

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500g

£160.00

€188

$208

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1kg

£280.00

€328

$364

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Catalog number FLA-01

Product

Fmoc-Arg(Pbf)-OH

more information

Prod. code / CAS#

FLR-01
154445-77-9

Structure

25g

£120.00

€141

$156

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100g

£200.00

€234

$260

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500g

£800.00

€936

$1040

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1kg

£1,350.00

€1580

$1755

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Molecular formula C34H40N4O7S

Molecular weight 648.77

Appearance White or off-white powder

Loss on drying ≤3.0%

Purity ≥98%

Optical rotation 5°± 2° (C=1, DMF)

Enantiomeric purity ≤0.5% L-Enantiomer

Product

Fmoc-Asn(Trt)-OH

more information

Prod. code / CAS#

FLN-01
132388-59-1

Structure

25g

£50.00

€59

$65

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100g

£120.00

€141

$156

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500g

£400.00

€468

$520

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1kg

£730.00

€855

$949

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Catalog number FLN-01

Product

Fmoc-Asp(OtBu)-OH

more information

Prod. code / CAS#

FLD-01
71989-14-5

Structure

25g

£55.00

€65

$72

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100g

£120.00

€141

$156

Added. View quote

500g

£420.00

€492

$546

Added. View quote

1kg

£760.00

€890

$988

Added. View quote

Catalog number FLD-01

Product

Fmoc-Cys(Trt)-OH

more information

Prod. code / CAS#

FLC-01
103213-32-7

Structure

25g

£55.00

€65

$72

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100g

£100.00

€117

$130

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500g

£420.00

€492

$546

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1kg

£720.00

€843

$936

Added. View quote

Catalog number FLC-01

Product

Fmoc-Gln(Trt)-OH

more information

Prod. code / CAS#

FLQ-01
132327-80-1

Structure

25g

£50.00

€59

$65

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100g

£125.00

€147

$163

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500g

£440.00

€515

$572

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1kg

£830.00

€972

$1079

Added. View quote

Catalog number FLQ-01

Product

Fmoc-Glu(OtBu)-OH

more information

Prod. code / CAS#

FLE-01
71989-18-9

Structure

25g

£55.00

€65

$72

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100g

£120.00

€141

$156

Added. View quote

500g

£530.00

€621

$689

Added. View quote

1kg

£720.00

€843

$936

Added. View quote

Catalog number FLE-01

Product

Fmoc-Gly-OH

more information

Prod. code / CAS#

FLG-01
29022-11-5

Structure

100g

£49.00

€58

$64

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500g

£165.00

€194

$215

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1kg

£270.00

€316

$351

Added. View quote

Catalog number FLG-01

Product

Fmoc-His(Trt)-OH

more information

Prod. code / CAS#

FLH-01
109425-51-6

Structure

25g

£55.00

€65

$72

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100g

£120.00

€141

$156

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500g

£400.00

€468

$520

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1kg

£730.00

€855

$949

Added. View quote

Catalog number FLH-01

Product

Fmoc-Ile-OH

more information

Prod. code / CAS#

FLI-01
71989-23-6

Structure

100g

£48.00

€57

$63

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500g

£170.00

€199

$221

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1kg

£270.00

€316

$351

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Catalog number FLI-01

Product

Fmoc-Leu-OH

more information

Prod. code / CAS#

FLL-01
35661-60-0

Structure

100g

£48.00

€57

$63

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500g

£180.00

€211

$234

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1kg

£320.00

€375

$416

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Catalog number FLL-01

Product

Fmoc-Lys(Boc)-OH

more information

Prod. code / CAS#

FLK-01
71989-26-9

Structure

25g

£55.00

€65

$72

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100g

£100.00

€117

$130

Added. View quote

500g

£370.00

€433

$481

Added. View quote

1kg

£650.00

€761

$845

Added. View quote

Catalog number FLK-01

Product

Fmoc-Met-OH

more information

Prod. code / CAS#

FLM-01
71989-28-1

Structure

100g

£48.00

€57

$63

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500g

£170.00

€199

$221

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1kg

£300.00

€351

$390

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Catalog number FLM-01

Product

Fmoc-Phe-OH

more information

Prod. code / CAS#

FLF-01
35661-40-6

Structure

100g

£48.00

€57

$63

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500g

£170.00

€199

$221

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1kg

£320.00

€375

$416

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Catalog number FLF-01

Product

Fmoc-Pro-OH

more information

Prod. code / CAS#

FLP-01
71989-31-6

Structure

100g

£50.00

€59

$65

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500g

£180.00

€211

$234

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1kg

£340.00

€398

$442

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Catalog number FLP-01

Product

Fmoc-Ser(But)-OH

more information

Prod. code / CAS#

FLS-01
71989-33-8

Structure

25g

£55.00

€65

$72

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100g

£130.00

€153

$169

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500g

£420.00

€492

$546

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1kg

£715.00

€837

$930

Added. View quote

Catalog number FLS-01

Product

Fmoc-Thr(But)-OH

more information

Prod. code / CAS#

FLT-01
71989-35-0

Structure

25g

£55.00

€65

$72

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100g

£130.00

€153

$169

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500g

£400.00

€468

$520

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1kg

£740.00

€866

$962

Added. View quote

Catalog number FLT-01

Product

Fmoc-Trp(Boc)-OH

more information

Prod. code / CAS#

FLW-01
143824-78-6

Structure

25g

£100.00

€117

$130

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100g

£250.00

€293

$325

Added. View quote

500g

£840.00

€983

$1092

Added. View quote

1kg

£1,400.00

€1638

$1820

Added. View quote

Catalog number FLW-01

Product

Fmoc-Tyr(But)-OH

more information

Prod. code / CAS#

FLY-01
71989-38-3

Structure

25g

£55.00

€65

$72

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100g

£140.00

€164

$182

Added. View quote

500g

£440.00

€515

$572

Added. View quote

1kg

£810.00

€948

$1053

Added. View quote

Catalog number FLY-01

Product

Fmoc-Val-OH

more information

Prod. code / CAS#

FLV-01
68858-20-8

Structure

100g

£48.00

€57

$63

Added. View quote

500g

£170.00

€199

$221

Added. View quote

1kg

£320.00

€375

$416

Added. View quote

Catalog number FLV-01