Fmoc-L-Amino Acids were first reported by Carpino in 1970. Peptide synthesis and cleavage conditions are milder with Fmoc amino acids than Boc amino acids. This protecting group offers also more flexibility for the modification of the peptide chain and more specificity in the cleavage of the side-chain protecting groups.

The Fmoc group is removed from Fmoc-peptide chain under basic conditions, thus allowing any acid labile resins to be used. The Fmoc group is usually removed using piperidine, which removes the Fmoc group and reacts with the deprotection byproduct, the dibenzofulvene, to prevent undesired side reactions and byproducts. This dibenzofulvene adduct allows the UV monitoring of the deprotection progression to be performed.

 

The Fmoc group has a limited stability towards tertiary amines such as DIEA, pyridine, this stability depends on base concentration, solvent and temperature.

Please click on the amino acid name to see the detailed description and CAS number.

All Fmoc-L-Amino Acids are also available in bulk quantities, please get in touch or request a quotation.

Product

Prod. code / CAS#

Structure

Product

Fmoc-Ala-OH*H2O

more information

Prod. code / CAS#

FLA-01
35661-39-3

Structure

100g

£44.00

€52

$63

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500g

£150.00

€176

$212

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1kg

£245.00

€287

$346

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Catalog number FLA-01

Product

Fmoc-Arg(Pbf)-OH

more information

Prod. code / CAS#

FLR-01
187618-60-6

Structure

25g

£113.00

€133

$160

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100g

£250.00

€293

$353

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500g

£800.00

€936

$1128

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1kg

£1,250.00

€1463

$1763

Added. View quote

Molecular formula C34H40N4O7S

Molecular weight 648.77

Appearance White or off-white powder

Loss on drying ≤3.0%

Purity ≥98%

Optical rotation 5°± 2° (C=1, DMF)

Enantiomeric purity ≤0.5% L-Enantiomer

Product

Fmoc-Asn(Trt)-OH

more information

Prod. code / CAS#

FLN-01
132388-59-1

Structure

25g

£45.00

€53

$64

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100g

£130.00

€153

$184

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500g

£385.00

€451

$543

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1kg

£715.00

€837

$1009

Added. View quote

Catalog number FLN-01

Product

Fmoc-Asp(OtBu)-OH

more information

Prod. code / CAS#

FLD-01
71989-14-5

Structure

25g

£45.00

€53

$64

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100g

£130.00

€153

$184

Added. View quote

500g

£385.00

€451

$543

Added. View quote

1kg

£715.00

€837

$1009

Added. View quote

Catalog number FLD-01

Product

Fmoc-Cys(Trt)-OH

more information

Prod. code / CAS#

FLC-01
103213-32-7

Structure

25g

£45.00

€53

$64

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100g

£100.00

€117

$141

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500g

£380.00

€445

$536

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1kg

£705.00

€825

$995

Added. View quote

Catalog number FLC-01

Product

Fmoc-Gln(Trt)-OH

more information

Prod. code / CAS#

FLQ-01
132327-80-1

Structure

25g

£45.00

€53

$64

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100g

£125.00

€147

$177

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500g

£410.00

€480

$579

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1kg

£760.00

€890

$1072

Added. View quote

Catalog number FLQ-01

Product

Fmoc-Glu(OtBu)-OH

more information

Prod. code / CAS#

FLE-01
71989-18-9

Structure

25g

£45.00

€53

$64

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100g

£125.00

€147

$177

Added. View quote

500g

£385.00

€451

$543

Added. View quote

1kg

£715.00

€837

$1009

Added. View quote

Catalog number FLE-01

Product

Fmoc-Gly-OH

more information

Prod. code / CAS#

FLG-01
29022-11-5

Structure

100g

£44.00

€52

$63

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500g

£150.00

€176

$212

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1kg

£245.00

€287

$346

Added. View quote

Catalog number FLG-01

Product

Fmoc-His(Trt)-OH

more information

Prod. code / CAS#

FLH-01
109425-51-6

Structure

25g

£45.00

€53

$64

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100g

£120.00

€141

$170

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500g

£385.00

€451

$543

Added. View quote

1kg

£715.00

€837

$1009

Added. View quote

Catalog number FLH-01

Product

Fmoc-Ile-OH

more information

Prod. code / CAS#

FLI-01
71989-23-6

Structure

100g

£44.00

€52

$63

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500g

£150.00

€176

$212

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1kg

£245.00

€287

$346

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Catalog number FLI-01

Product

Fmoc-Leu-OH

more information

Prod. code / CAS#

FLL-01
35661-60-0

Structure

100g

£44.00

€52

$63

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500g

£150.00

€176

$212

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1kg

£245.00

€287

$346

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Catalog number FLL-01

Product

Fmoc-Lys(Boc)-OH

more information

Prod. code / CAS#

FLK-01
71989-26-9

Structure

25g

£40.00

€47

$57

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100g

£100.00

€117

$141

Added. View quote

500g

£340.00

€398

$480

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1kg

£650.00

€761

$917

Added. View quote

Catalog number FLK-01

Product

Fmoc-Met-OH

more information

Prod. code / CAS#

FLM-01
71989-28-1

Structure

100g

£44.00

€52

$63

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500g

£150.00

€176

$212

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1kg

£245.00

€287

$346

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Catalog number FLM-01

Product

Fmoc-Phe-OH

more information

Prod. code / CAS#

FLF-01
35661-40-6

Structure

100g

£44.00

€52

$63

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500g

£150.00

€176

$212

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1kg

£245.00

€287

$346

Added. View quote

Catalog number FLF-01

Product

Fmoc-Pro-OH

more information

Prod. code / CAS#

FLP-01
71989-31-6

Structure

100g

£44.00

€52

$63

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500g

£150.00

€176

$212

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1kg

£245.00

€287

$346

Added. View quote

Catalog number FLP-01

Product

Fmoc-Ser(But)-OH

more information

Prod. code / CAS#

FLS-01
71989-33-8

Structure

25g

£45.00

€53

$64

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100g

£130.00

€153

$184

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500g

£385.00

€451

$543

Added. View quote

1kg

£715.00

€837

$1009

Added. View quote

Catalog number FLS-01

Product

Fmoc-Thr(But)-OH

more information

Prod. code / CAS#

FLT-01
71989-35-0

Structure

25g

£45.00

€53

$64

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100g

£130.00

€153

$184

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500g

£385.00

€451

$543

Added. View quote

1kg

£715.00

€837

$1009

Added. View quote

Catalog number FLT-01

Product

Fmoc-Trp(Boc)-OH

more information

Prod. code / CAS#

FLW-01
143824-78-6

Structure

25g

£100.00

€117

$141

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100g

£250.00

€293

$353

Added. View quote

500g

£810.00

€948

$1143

Added. View quote

1kg

£1,275.00

€1492

$1798

Added. View quote

Catalog number FLW-01

Product

Fmoc-Tyr(But)-OH

more information

Prod. code / CAS#

FLY-01
71989-38-3

Structure

25g

£45.00

€53

$64

Added. View quote

100g

£130.00

€153

$184

Added. View quote

500g

£410.00

€480

$579

Added. View quote

1kg

£760.00

€890

$1072

Added. View quote

Catalog number FLY-01

Product

Fmoc-Val-OH

more information

Prod. code / CAS#

FLV-01
68858-20-8

Structure

100g

£44.00

€52

$63

Added. View quote

500g

£150.00

€176

$212

Added. View quote

1kg

£245.00

€287

$346

Added. View quote

Catalog number FLV-01