Fmoc-D-Amino Acids

Available for fast delivery – contact us now to place an order or to request a quotation info@activotec.com or tel: +44 (0)1223 260008

Fmoc-D-amino acids

Activotec is offers high purity Fmoc-D-Amino acids to its clients! With competitive prices and the highest purity on the market, they are available from small to bulk quantities.

Fmoc-D-Amino Acids from Activotec are greater than 99% pure and competitively priced.  Fmoc-D-amino acids are not used as frequently as the corresponding L-isomers because D-amino acids do not occur in the proteins and peptides produced by higher organisms. However D-amino acids are often found in the peptidoglycans contained in the cell membranes of many microbes.  Many natural and synthetic peptides containing D-amino acids possess strong antimicrobial properties. Beside antimicrobial properties, introducing D-amino acids into a synthetic peptide can make the peptide less susceptible to enzymatic degradation and improves its drug characteristics. For example D-amino acids are often used to increase the stability of a peptide to proteases.  D-amino acids can be incorporated in place of the natural L-amino acids, either at a specific position, or throughout the whole peptide.

Cyclic analogs of small bioactive peptides are being studied as potential drug targets.  These small cyclic peptides often contain at least one D-amino acid.  Including a D-amino acid in the linear precursor peptide promotes efficient cyclization.

All Fmoc-D-Amino Acids are also available in bulk quantities.  Please e-mail info@activotec.com for a bulk quotation.