High purity unusual amino acids

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Fmoc-D-amino acids

Activotec is now proud to offer high purity Fmoc-D-Amino acids to its clients! With competitive prices and highest purity on the market, they are available from small to bulk quantities.

Fmoc-D-Amino Acids from Activotec are greater than 99% pure and competitively priced.  Fmoc-D-amino acids are not used as frequently as the corresponding L-isomers because D-amino acids do not occur in the proteins and peptides produced by higher organisms. However D-amino acids are often found in the peptidoglycans contained in the cell membranes of many microbes.  Many natural and synthetic peptides containing D-amino acids possess strong antimicrobial properties. Beside antimicrobial properties, introducing D-amino acids into a synthetic peptide can make the peptide less susceptible to enzymatic degradation and improves its drug characteristics. For example D-amino acids are often used to increase the stability of a peptide to proteases.  D-amino acids can be incorporated in place of the natural L-amino acids, either at a specific position, or throughout the whole peptide.

Cyclic analogs of small bioactive peptides are being studied as potential drug targets.  These small cyclic peptides often contain at least one D-amino acid.  Including a D-amino acid in the linear precursor peptide promotes efficient cyclization.

All Fmoc-D-Amino Acids are also available in bulk quantities.  Please e-mail Activotec at for a bulk quotation.

Fmoc-D-Tyr(4-ET)-OH  FDY-02                  440 €          £370                                      1,100€     £920.00

L Unusual Amino Acid            Product Code                      5g                                   25g             

Fmoc-L-Tyr(4-Et)-OH        FLY-02                 410€   £350

Boc-Ser(tBu)-OH, DCHA      BLS-01            100g - 650€    £550

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