Unusual Amino Acids

High purity unusual amino acids

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Fmoc-D-amino acids

Activotec is now proud to offer high purity Fmoc-D-Amino acids to its clients! With competitive prices and highest purity on the market, they are available from small to bulk quantities.

Fmoc-D-Amino Acids from Activotec are greater than 99% pure and competitively priced.  Fmoc-D-amino acids are not used as frequently as the corresponding L-isomers because D-amino acids do not occur in the proteins and peptides produced by higher organisms. However D-amino acids are often found in the peptidoglycans contained in the cell membranes of many microbes.  Many natural and synthetic peptides containing D-amino acids possess strong antimicrobial properties. Beside antimicrobial properties, introducing D-amino acids into a synthetic peptide can make the peptide less susceptible to enzymatic degradation and improves its drug characteristics. For example D-amino acids are often used to increase the stability of a peptide to proteases.  D-amino acids can be incorporated in place of the natural L-amino acids, either at a specific position, or throughout the whole peptide.

Cyclic analogs of small bioactive peptides are being studied as potential drug targets.  These small cyclic peptides often contain at least one D-amino acid.  Including a D-amino acid in the linear precursor peptide promotes efficient cyclization.

All Fmoc-D-Amino Acids are also available in bulk quantities.  Please e-mail Activotec at for a bulk quotation.

 

D Amino Acid Product code 5 g 10 g 25 g 100g
Fmoc-D-Ala-OH*H2O FDA-01 25 € £21 45 € £38 70 € £58 175 € £146
Fmoc-D-Arg(Pbf)-OH FDR-01 80 € £67 150 € £125 320 € £267 900 € £750
Fmoc-D-Asn(Trt)-OH FDN-01 40 € £33 70 € £58 155 € £129  460 € £383
Fmoc-D-Asp(OtBu)-OH FDD-01 40 € £33 75 € £54 165 € £121  500 € £417
Fmoc-D-Cys(Trt)-OH FDC-01 40 € £33 75 € £63 165 € £138  500 € £417
Fmoc-D-Gln(Trt)-OH FDQ-01 70 € £58 110 € £92 235 € £196  650 € £542
Fmoc-D-Glu(OtBu)-OH FDE-01 70 € £58 110 € £92 235 € £196 650 € £542
Fmoc-D-His(Trt)-OH FDH-01 55 € £46 90 € £75 200 € £167  450 € £375
Fmoc-D-Ile-OH FDI-02 185 € £633 on request on request on request on request on request on request
Fmoc-D-Leu-OH FDL-01 30 € £25 55 € £46 80 € £67 190 € £158
Fmoc-D-Lys(Boc)-OH FDK-01 45 € £38 80 € £67 140 € £117 440 € £367
Fmoc-D-Met-OH FDM-01 30 € £25 55 € £46 80 € £67 190 € £158
Fmoc-D-Phe-OH FDF-01 30 € £25 55 € £46 80 € £67 190 € £158
Fmoc-D-Pro-OH FDP-01 30 € £25 55 € £46 80 € £67 190 € £158
Fmoc-D-Ser(tBu)-OH FDS-01 60 € £50 105 € £88 235 € £196 630 € £525
Fmoc-D-Thr(tBu)-OH FDT-01 85 € £71 135 € £113 330 € £275 700€ £583
Fmoc-D-Trp(Boc)-OH FDW-01 110 € £92 175 € £146 395 € £329 1,025 € £854
Fmoc-D-Tyr(tBu)-OH FDY-01 85 € £71 135 € £113 330 € £275 700 € £583
Fmoc-D-Val-OH FDV-01 30 € £25 55 € £46 80 € £67 190 € £158

Fmoc-D-Tyr(4-ET)-OH  FDY-02                  440 €          £370                                      1,100€     £920.00

L Unusual Amino Acid            Product Code                      5g                                   25g             

Fmoc-Aib-OH FLU-05 42 €   £35 80 €   £65    
Fmoc-6-Ahx-OH FLU-03 42 €   £35 55 €   £45    
Fmoc-L-Cha-OH FLU-06 110 €   £90 350 €   £290    
Fmoc-L-Dap(Boc)-OH FLU-07 145 €   £120 465 €   £385    
Fmoc-L-homoArg(Pbf)-OH FLU-08 440 €   £350 1250 €   £1050    
Fmoc-L-Lys(Dde)-OH FLK-04 365 €   £304 POA      POA    
Fmoc-L-Lys(Fmoc)-OH FLK-05     110 €   £90    
Fmoc-L-Lys(ivDde)-OH FLK-08 330€   £275 POA    POA    
Fmoc-L-Lys(Mtt)-OH FLK-09 110 €   £90 410 €   £340    
Fmoc-L-Nle-OH FLU-09 65 €   £54 145 €   £120    
Fmoc-L-Nva-OH FLU-10 50 €   £42 140  €   £115    
Fmoc-L-Oic-OH FLU-11 750 €   £625 POA     POA    
Fmoc-L-Orn(Boc)-OH FLO-01 45 €   £38 140 €   £115    
Fmoc-L-4-Cl-Phe-OH FLU-12 150 €   £125 390 €   £325    
Fmoc-L-Sar-OH FLU-14 42 €   £35 115 €   £95    

Fmoc-L-Tyr(4-Et)-OH        FLY-02                 410€   £350

Boc-Ser(tBu)-OH, DCHA      BLS-01            100g - 650€    £550

Phospho Amino Acids Product code 1 g 5 g
Fmoc-Ser(PO(OBzl)OH)-OH FLS-09 135 € £110 320 € £265
Fmoc-Thr(PO(OBzl)OH)-OH FLT-09 135 € £110 320 € £265
Fmoc-Tyr(PO(OBzl)OH)-OH FLY-09 135 € £110 320 € £265

Fluorescent Dyes

Reagents Product code 500 mg
5-FAM (5-Carboxyfluorescein) 1122 260 € £215
5-TAMRA (5-Carboxytetramethylrhodamine) 1123 690 € £575