Fmoc Protected Amino Acids

Fmoc Protected Amino Acids - 25g to kg's

Fmoc-L-Amino Acids were first reported by Carpino in 1970. Peptide synthesis and cleavage conditions are milder with Fmoc amino acids than Boc amino acids. This protecting group offers also more flexibility for the modification of the peptide chain and more specificity in the cleavage of the side-chain protecting groups.

The Fmoc group is removed from Fmoc-peptide chain under basic conditions, thus allowing any acid labile resins to be used. The Fmoc group is usually removed using piperidine, which removes the Fmoc group and reacts with the deprotection byproduct, the dibenzofulvene, to prevent undesired side reactions and byproducts. This dibenzofulvene adduct allows the UV monitoring of the deprotection progression to be performed. 

The Fmoc group has a limited stability towards tertiary amines such as DIEA, pyridine, this stability depends on base concentration, solvent and temperature.

Please click on the amino acid name to see the detailed description and CAS number.

All Fmoc-L-Amino Acids are also available in bulk quantities.  Please This e-mail address is being protected from spambots. You need JavaScript enabled to view it Activotec for a bulk quotation.

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Amino acid           Product code                  25g                               100g_____                      500g_    __       ___  ___1kg__

Fmoc-Ala-OH*H2O FLA-01       50 € £44   180 € £150   295 € £245
Fmoc-Arg(Pbf)-OH FLR-01 130 € £115   290 € £250   960 € £800   1500 € £1,250
Fmoc-Asn(Trt)-OH FLN-01 50 € £45   125 € £130   465 € £385   860 € £715
Fmoc-Asp(OtBu)-OH FLD-01 50 € £45   150 € £130   465 € £385   860 € £715
Fmoc-Cys(Trt)-OH FLC-01 50 € £45   150 € £100   455 € £380   750 € £705
Fmoc-Gln(Trt)-OH FLQ-01 50 € £45   145 € £125   495 € £410   915 € £760
Fmoc-Glu(OtBu)-OH FLE-01 50 € £45   145 € £125   465 € £385   860 € £715
Fmoc-Gly-OH            FLG-01       50 € £44   180 € £150   295 € £245
Fmoc-His(Trt)-OH FLH-01 50 € £45   135 € £120   465 € £385   860 € £715
Fmoc-Ile-OH                FLI-01       50 € £44   180 € £150   295 € £245
Fmoc-Leu-OH              FLL-01       50 € £44   180 € £150   295 € £245
Fmoc-Lys(Boc)-OH FLK-01 45 € £40   115 € £100   410 € £340   780 € £650
Fmoc-Met-OH            FLM-01       50 € £44   180 € £150   295 € £245
Fmoc-Phe-OH            FLF-01       50 € £44   180 € £150   295 € £245
Fmoc-Pro-OH            FLP-01       50 € £44   180 € £150   295 € £245
Fmoc-Ser(But)-OH FLS-01 50 € £45   150 € £130   465 € £385   860 € £715
Fmoc-Thr(But)-OH FLT-01 50 € £45   150 € £130   465 € £385   860 € £715
Fmoc-Trp(Boc)-OH FLW-01 1150 € £100   290 € £250   975 € £810   1530 € £1275
Fmoc-Tyr(But)-OH FLY-01 50 € £45   150 € £130   495 € £410   915 € £760
Fmoc-Val-OH              FLV-01       50 € £44   180 € £150   295 € £245